枸杞多糖对脑缺血再灌流小鼠学习、记忆的影响

EFFECT OF LYCIUM BARBARUM POLYSACCHARIDES ON LEARNING & MEMORY IN MICE

本文采用结扎小鼠双侧颈总动脉１ｈ，同时在距尾尖１ｃｍ处剪断其尾放血数滴，继之再灌流２４ｈ，造成小鼠全脑缺血再灌流的损伤。观察枸杞多糖对脑缺血再灌流小鼠学习、记忆能力的影响。结果表明，枸杞多糖可显著提高脑缺血再灌流小鼠的学习、记忆能力，并促进其学习、记忆能力的恢复。

By one hour ligation of the mice′s bilateral carotid arteriesand then 24 hours reperfusion,the effects of Lycium barbarum polysaccha-rides(LBP)on learning and memory of mice with 1h cerebral ischemiafollowed by reperfusion 24 hours were evaluated.The results indicated thatLBP could improve these animals′learning and memory ability.