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钛-抗坏血酸螯合物的喂养繁殖致畸实验研究

Study on Teratogenic Effect of Titanium Ascorbate in Rats
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摘要 用含0.0156%~1%钛-抗坏血酸螯合物饮水对S.D.大鼠进行了90天喂养实验、喂养繁殖和喂养致畸实验。结果表明大鼠成鼠和幼鼠的生长发育、雌鼠受孕率、孕鼠体重、胚胎体重和骨化程度均未受明显影响,也未引起胚胎外观及内脏畸形。 Jiangxi Institute of Industry Hygiene,Nanchang, Jiangxi 330006 P.R. China A feeding test in 90 days, feeding reproduction test and teratogenic reproduction test have been conducted in SD rats.The rats,were fed with 90.156%~1%titanium ascorbate in the drinking water.The results showed that no obvious adverse effects were found on the growth of the adult rats and their off springs,the rates of gestation,the average weight of the pregnant rats,the rates of resorbed and dead embryos,the average litter weight and skeletal development. No external and internal malformation in the offsprings was found due to treatmeat with titanium ascorbate .
出处 《劳动医学》 1995年第2期6-8,19,共4页
关键词 钛-抗坏血酸螯合物 繁殖能力 致畸作用 动物实验 药物毒性 Titanium ascorbate Teratogenesis Feeding reproduction test
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