2013-2017年柳州市柳南区出生缺陷人群监测资料分析

Analysis on the Population Based Monitoring Data of Birth Defect in Liunan District of Liuzhou City From 2013 to 2017

目的了解柳州市柳南区人群出生缺陷的发生情况,为制定干预措施提供参考依据。方法对柳州市妇幼卫生信息系统中收集的柳州市柳南区出生缺陷人群监测资料进行统计分析,率和构成比的比较采用χ~2检验。结果 2013-2017年,柳南区共登记围产儿36 330例,发现的出生缺陷儿为894例,人群出生缺陷总发生率为24.61‰,5年来缺陷发生率呈现下降趋势,不同年份的发生率差异有统计学意义(χ~2=41.746,P=0.000);男性发生率(26.33‰)高于女性(22.59‰),本地常住(26.71‰)高于非本地常住(22.98‰),差异均有统计学意义(P<0.01);但不同年龄组产妇所生婴儿的出生缺陷发生率无统计学差异(χ~2=3.762,P=0.439)。出生缺陷发生率前5位分别为先天性心脏病(8.83‰)、多指/趾(2.89‰)、睾丸鞘膜积液(1.65‰)、外耳其他畸形(1.21‰)、并指/趾(0.79‰)。结论柳州市柳南区人群出生缺陷发生率处于较高水平,需进一步从三级预防角度出发,降低出生缺陷的发生率。

Objective To investigate the incidence of birth defects in population of Liunan District,Liuzhou,so as to provide a scientific basis for formulating intervention measures.Methods The monitoring data of the population with birth defects in Liunan District of Liuzhou collected from the Maternal and Child Health Information System of Liuzhou were statistically analyzed.Results A total of 894 cases with birth defect were detected from 36 330 births in Liunan district from 2013 to 2017,the overall incidence of birth defect was 24.61‰,with a downtrend showed in last five years,the incidence between different years were statistically different(χ~2=41.746,P=0.000).The rates of birth defects in male(26.33‰)was higher than that of female(22.59‰),incidence of birth defects among longtime residents(26.71‰)was higher than that of those migrants(22.98‰),there were significantly different incidence of birth defects between different gender as well as between longtime residents and migrants(P<0.01).There was no statistical different incidence of birth defects among different age groups of mother(χ~2=3.762,P=0.439).The top five birth defects were congenital heart diseases(8.83‰),multiple fingers/toes(2.89‰),hydrocele of testis(1.65‰),other outer ear deformities(1.21‰)and syndactylia(0.79‰),respectively.Conclusion The incidence of birth defect in population from Liunan district was relatively high.It is necessary to further reduce the occurrence of birth defects from the perspective of tertiary prevention.