摘要
本文按国际上远交群小鼠的遗传监测和控制的要求，对Ｓｉｂｐ：ＫＭ小鼠进行育种繁殖、遗传背景和生物学特性等多方面的研究。统计分析该小鼠繁殖性能，绘制了生长曲线。测定２４个生化标志基因位点，其中１１个位点呈多态型，平均杂合率为０．２０９。该小鼠下颌骨形态分析的部分判别函数值（占４４％）超过均值±２ＳＤ，呈弥散分布。该小鼠Ｈ－２组织相容合体，具有１０种Ｉ类私有抗原，１７种表现型。此外还测定该小鼠形态数据、部分血液学数据和整体分析，为Ｓｉｂｐ：ＫＭ小鼠推广应用提供技术数据。
he genetic background, reproductive performance and biologicalcharacteristics were studied on outbred stock of Sibp : KM mouse. Inaccordance with The Cenetic Control Measures in Outbred Stock, thestatistic analysis of the reproductive performance and the growth curvewere made.24 biochemical genetic markers were tested.The average hetero-zygosity was found to be 0.209. The mandible morphimetric analysis reve-aled that 44% of the DF values exceeded 2SD. H-2 polymorphism wasalso studied, 10 class I private antigens with 17 phenotypes were found inthis colony. Morphometric data, including body length, ulna length, bodyweight. were measured,and basic hematological data and total body analy-sis were tested.
出处
《中国实验动物学报》
CAS
CSCD
1995年第1期1-6,共6页
Acta Laboratorium Animalis Scientia Sinica
