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心肌细胞外基质降解与心肌梗死 被引量：1

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摘要 在一些心血管疾病的发展过程中,除心肌细胞本身结构、代谢及功能异常外,心脏间质组织也发生异常改变.20世纪80年代以前,心血管疾病的研究多集中在对心肌细胞本身的改变上;80年代以后,许多实验结果表明:整个心脏泵功能的异常不仅取决于心肌细胞本身的改变,而且还发现心肌细胞外基质(Extracellular Matrix,ECM)尤其是心肌胶原的异常改变,在心血管疾病的发病机制中起着重要的作用.
作者 白江涛 陆凤翔
机构地区 南京医科大学第一附属医院心脏科
出处 《中国心血管病研究》 CAS 2003年第3期223-226,共4页 Chinese Journal of Cardiovascular Research
关键词 心肌细胞 基质降解 心肌梗死 心血管疾病
分类号 R542.22 [医药卫生—心血管疾病]
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参考文献17

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同被引文献14

  • 1吴旻,李玉光,闫纯英,张钰,许端敏.基质金属蛋白酶和氧化应激在大鼠动脉粥样硬化中的表达[J].中国心血管病研究,2007,5(1):55-57. 被引量：8
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  • 7Mason DP, Kenagy RD, Hasenstab D, et al. Matrix metallopro- teinase-9 over expression enhances vascular smooth muscle cell migration and alters remodeling in the injured rat carotid artery. Circ Res, 1999,85 : 1179-1185.
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中国心血管病研究
2003年 第3期

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