甲亢伴周期性麻痹^(131)I治疗疗效观察(附31例分析)

The therapeutical investigation of ^(131) I for hyperthyroidism combined with periodic paralysis

目的 评价甲亢伴周期性麻痹 1 31 I治疗的疗效。方法 31例甲亢伴周期性麻痹的患者采取 1 31 I治疗 ,所有病例至少随访半年以上 ,按治疗的效果分为治愈、部分缓解、甲低、无效四组 ,统计各组的发生率 ,对其结果进行分析。结果 31例患者治愈 2 2例 ,占 71 .0 % ;甲低 5例 ,占 1 6 .1 % ;无效 4例 ,占 1 2 .9%。结论 1 31 I治疗甲亢伴周期性麻痹具有治愈率高、简单、安全等特点 ,能克服抗甲状腺药物或手术治疗的某些不足 ,治疗后有一定的甲低发生率。在 1 31 I治疗时 ,应尽可能多考虑可能影响 1 31 I治疗剂量制定的因素 。

Objective To investigate the therapeutical effect of 131 I for hyperthyroidism combined with periodic paralysis.Methods 31 cases of hyperthyroidism combined with periodic paralysis received 131 I treatment,and all cases were followed up for at least half a year.Therapeutical effect were classified as cure,partly remission,hypothyroidism and ineffective.Results\ 22 cases(71 0%)were cured,hypothyroidism happened in 5 cases and 4 cases were ineffective.Conclusion\ 131 I treatment for hyperthyroidism combined with periodic paralysis is a safe,simple and effective method.It can overcome the shortcomings of surgery and drug,but hypothyroidism could happen in some patients.Therefore,the factors of affecting dosage of 131 I should be seriously considered when this method is applied to patients.