烯丙醇化合物的不对称环氧化

Asymmetric Epoxidations of Allylic Alcohols

本文报道了三个脂肪族烯丙醇化合物(1-3)的不对称环氧化反应。由反式烯丙醇2得到的反式烯丙醇环氧化合物2a的对映体过量大于由顺式烯丙醇1得到的环氧化合物1a的对映体过量。叔羟基二取代烯丙醇3经不对称环氧化生成的3a,其对映体过量只有4%。

The asymmetric epoxidation of three allylic alcohols (1-3) are described.The enantiomeric excess of the epoxy alcohol 2a (obtained from the trans-allylic alcohol2) was greater than that of la (obtained from the cis-allylic alcohol 1).The asymmetricepoxidation of the tertiary allylic alcohol 3 yielded 3a,of which the enantiomeric excesswas only 4%.