双(α-次甲基羰基)化合物氧化反应的研究

Study on the Oxidation of Bis(α-methylene carbonyl) Compounds

几种双(α-次甲基羰基)化合物分别用两种氧化体系DMSO和HBr或DMSO,HCI和KI,进行氧化,得到了相应的双(1,2-二羰基)化合物。对所得到的产物进行了元素分析、质谱和1~H核磁共振谱测定。实验结果表明氧化产物的产量高,操作简便,原料价廉,为大量制备这类化合物创造了条件。

The oxidation of bis(α-methylene carbonyl) compounds was studied byusing (i) DMSO and HBr or (ii) DMSO,HCl and KI as oxidizing agents.It is foundthat these reactions using DMSO with a suitable amount of HBr or HCl with KI resultin higher yield and higher purity of bis(1,2-dicarbonyl) compounds as compared withthe commonly used oxidizing agents,such as SeO_2. The yield and the melting points of these products as well as the elemental analysis,mass spectroscopy and NMR spectroscopy are reported in this paper.