DNA倍体定量分析技术在肺癌诊断中的相关研究进展

Advances in research on DNA ploidy quantitative analysis in the diagnosis of lung cancer

近年来,肺癌的发病率和死亡率均位居各类恶性肿瘤之首,并呈逐年上升趋势。对高危人群进行早期发现、早期诊断、早期预防治疗等是降低死亡率的重要途径。有研究表明,早期诊断并及时有效地治疗能使Ⅰ期肺癌患者的5年生存率达到90%,但仅依靠肿瘤标志物和影像学检查仍不能很好地提高肺癌早期诊断率。文章就DNA倍体定量分析技术在肺癌诊断中的相关研究进展进行综述,为临床肺癌早期诊断提供参考。

In recent years,the incidence and mortality of lung cancer ranks first among all kinds of malignant tumors,and it is increasing year by year.Early detection,early diagnosis,early prevention and treatment of high-risk groups are important ways to reduce mortality.Studies have shown that early diagnosis and timely and effective treatment can make the 5-year survival rate of patients with stage I lung cancer reach 90%,but relying only on tumor markers and imaging examination can not improve the early diagnosis rate of lung cancer.This article reviews the research progress of DNA ploidy quantitative analysis in the diagnosis of lung cancer,and provides a reference for the early diagnosis of clinical lung cancer.