摘要
目的:观察在新生儿监护病房开展无创辅助通气的临床效果。方法:选取笔者所在医院2017年1月-2018年12月新生儿监护病房收治的52例呼吸窘迫综合征患儿,随机分为对照组(n=26,采取固尔舒联合常规机械通气治疗)与观察组(n=26,固尔舒联合经鼻正压辅助通气治疗),对两组临床疗效及相关指标进行观察。结果:观察组有效率与对照组比较差异无统计学意义(P>0.05);观察组患儿住院时间、通气时间均较对照组明显要短(P<0.05);在治疗前,两组患儿动脉血气指标比较差异无统计学意义(P>0.05),治疗12、24 h,两组患儿Pa O2/Fi O2、Pa O2和p H值均较治疗前明显提升,Pa CO2值出现下降,差异有统计学意义(P<0.05),在同一时间点,两组各项动脉血气指标比较差异无统计学意义(P>0.05);在并发症发生率上,观察组较对照组明显要低(P<0.05)。结论:在新生儿监护病房中对呼吸窘迫患儿采取无创辅助通气,疗效显著,且并发症少,值得推广使用。
Objective:To study the clinical effect of non-invasive mechanical ventilation in intensive care unit neonates.Method:From January 2017 to December 2018,52 respiratory distress syndrome(RDS) neonates treated in ICU were selected and randomly assigned to the control group(n=26) and the observation group(n=26).The control group was served as Curosurf plus conventional mechanical ventilation.The observation group was served as Curosurf plus nasal intermittent positive pressure ventilation.The clinical effect and indicators were probed.Result:The effective rate between group was not significantly different(P>0.05),the hospitalization time and ventilation time in the observation group was shorter than control group(P<0.05),before treatment,arterial blood gas indicators between groups were basically consistent(P>0.05),after 12 h and 24 h of treatment,the values of PaO2/FiO2,PaO2 and pH for two groups were sharply increased while the values of PaCO2 were sharply declined(P<0.05),at the same time point,arterial blood gas indicators between groups were not significantly different(P>0.05),the complication rate in the observation group was lower than control group(P<0.05).Conclusion:The non-invasive mechanical ventilation has an obvious effect in RDS neonates,can reduce the complication rate.It is worthy of clinical promotion and application.
作者
林炎浩
LIN Yanhao(Heping County Maternal and Child Health Hospital,Heping 517200,China)
出处
《中外医学研究》
2019年第8期14-16,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
新生儿监护病房
无创机械通气
早产儿
呼吸窘迫综合征
Intensive care unit
Non-invasive mechanical ventilation
Premature
Respiratory distress syndrome