泛昔洛韦、甘露聚糖肽联合氦氖激光治疗生殖器疱疹的效果观察

Observation on the Efficacy of Famciclovir,Mannose Peptide Combined with He-Ne Laser in Treatment of Genital Herpes

目的:观察泛昔洛韦、甘露聚糖肽联合氦氖激光治疗生殖器疱疹的临床效果。方法:选择2013年4月-2018年4月笔者所在医院收治的生殖器疱疹患者79例,随机分为治疗组和对照组。对照组39例,口服泛昔洛韦和甘露聚糖肽治疗;治疗组40例,口服泛昔洛韦和甘露聚糖肽同时联合氦氖激光局部照射治疗。对比两组临床疗效,观察两组患者临床症状及体征持续时间,记录治疗期间不良反应事件。结果:治疗组治疗总有效率(95.00%)高于对照组(79.49%),差异有统计学意义(P<0.05);治疗组患者瘙痒、灼烧、水疱、糜烂等症状体征消退时间均早于对照组,差异均有统计学意义(P<0.05);两组均未出现严重不良反应。结论:泛昔洛韦、甘露聚糖肽药物联合氦氖激光局部照射治疗生殖器疱疹临床效果优于单纯口服泛昔洛韦和甘露聚糖肽,皮损恢复缓解速度快,值得推广。

Objective:To investigate the efficacy of Famciclovir,Mannose Peptide and He-Ne laser on genital herpes.Method:A total of 79 patients with genital herpes admitted to our hospital from April 2013 to April 2018 were selected and randomly divided into treatment group and control group.In the control group,39 patients were treated with Famciclovir and Mannose Peptide orally.In the treatment group,40 cases were treated by oral administration of Famciclovir and Mannose Peptide combined with He-Ne laser local irradiation.The clinical efficacy of the two groups was compared,the duration of clinical symptoms and signs of the two groups were observed,and adverse reaction events during treatment were recorded.Result:The effective rate of the treatment group was significantly higher than that in the control group,the differences were statistically significant(P<0.05).The regression time of itching,burning,blister,erosion in the treatment group were significantly earlier than those in the control group(P<0.05).There was no serious adverse reactions occurred in the two groups of patients.Conclusion:The clinical efficacy of Fanciclovir and Mannose Peptide combined with He-Ne laser irradiation in the treatment of genitalia herpes is better than that of oral Fanciclovir and Mannose Peptide alone.The recovery rate of skin lesions is faster and it is worth popularizing.