胆囊结石患者腹腔镜下胆囊切除术围术期血清胆红素水平和创伤应激指标变化分析

Analysis of Perioperative Serum Bilirubin Level and Traumatic Stress Index in Patients with Gallstones Undergoing Laparoscopic Cholecystectomy

目的:分析胆囊结石患者腹腔镜下胆囊切除术围术期血清胆红素水平和创伤应激指标的变化情况。方法:选取85例胆囊结石患者,随机分为对照组(41例,开腹胆囊切除术)、研究组(44例,腹腔镜下胆囊切除术)。比较两组围术期血清胆红素水平、创伤应激指标。结果:术后即刻、术后2 d研究组血清总胆红素、直接胆红素水平、肾上腺素、皮质醇、空腹血糖、C反应蛋白水平均低于对照组,差异均有统计学意义(P<0.05)。结论:胆囊结石患者腹腔镜下胆囊切除术可减少对围术期血清胆红素水平和创伤应激指标的影响。

Objective:To analyze the changes of serum bilirubin level and traumatic stress index during laparoscopic cholecystectomy in patients with gallstone.Method:A total of 85 patients with gallstones were randomly divided into the control group(41 cases,open cholecystectomy)and the study group(44 cases,laparoscopic cholecystectomy).Perioperative serum bilirubin levels and traumatic stress were compared between the two groups.Result:Immediately after operation and 2 days after operation,the levels of serum total bilirubin,direct bilirubin,epinephrine,cortisol,empty abdominal blood glucose and C-reactive protein in the study group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Laparoscopic cholecystectomy in patients with gallstones can reduce the effects of perioperative serum bilirubin levels and traumatic stress indicators.