胎盘蛋白13联合多普勒超声早期预测子痫前期的临床研究被引量：2

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摘要目的研究胎盘蛋白13(PP13)联合多普勒超声对子痫前期进行预测的临床效果。方法选取2013.12-2015.12月在本院产科门诊定期产检并在本院分娩的单胎妊娠孕妇245例作为研究对象,根据检查结果将其分为正常妊娠组和子痫前期组,采用ELISA法测定孕11-14周血清PP13的浓度,孕22-24周进行超声测定子宫动脉血流参数指标,分析上述两项指标与子痫前期的相关性,使用ROC曲线分析并计算出两项结果的特异性与敏感度。结果子痫前期孕妇的胎盘蛋白13明显低于正常妊娠组,差异有显著性(P<0.05),ROC曲线分析显示,胎盘蛋白13联合多普勒超声的特异度为86%,灵敏度为82%。结论胎盘蛋白13联合多普勒超声对于预测子痫前期具有重要意义,预测的可靠性得到大幅提升,因此对于临床上的早期预测子痫前期具有重要作用。

作者曾晓玲雷后康张昭萍

机构地区贵州医科大学附属医院妇产科

出处《中国医疗设备》 2016年第S1期25-26,共2页 China Medical Devices

基金贵阳市科技局课题(筑科合同【2012103】30号)

关键词子痫前期胎盘蛋白13 多普勒超声预测

分类号 R714.244 [医药卫生—妇产科学]

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