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半髋置换术使用氨甲环酸的安全性和有效性临床研究

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摘要 目的对老年性股骨颈骨折患者行半髋置换术围手术期应用氨甲环酸的效果与安全性进行分析。方法将我院接受半髋置换术治疗的80例患者进行随机分组,每组20例进行比较:A组于切皮前静脉输入氨甲环酸1g,B组于切皮前静脉输入0.5g、手术结束时关节腔注入氨甲环酸0.5g,夹毕引流管2小时,C组于手术结束时关节腔注入氨甲环酸1g,夹毕引流管2小时,D组术前输入等量生理盐水100ml,比对相关观察指标。结果 A组术中出血量最少,且A、B组术中出血量较C、D组少;与D组比对,A、B、C三组术后24小时与48小时引流量、总红细胞丢失量、输血率均明显较少。四组的DVT及PE发生情况,凝血功能相关指标比对则没有没有差异(P>0.05)。结论将氨甲环酸应用在半髋置换术中止血安全、有效,且采用静脉联合关节腔给药方式,效果更好。
作者 陈小光
出处 《中国医疗设备》 2016年第S1期40-40,共1页 China Medical Devices
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