盐酸氟桂利嗪联合长春西汀注射液治疗眩晕综合征的疗效观察

The efficacy of flunarizine hydrochloride combined with vinpocetine injecta in treatment of vertigo syndrome

目的观察盐酸氟桂利嗪联合长春西汀注射液治疗眩晕综合征的临床疗效。方法选择2014年9月至2015年7月收治于本科室的102例眩晕综合征患者为研究对象,随机分为观察组与对照组,每组51例。对照组采用长春西汀注射液治疗,观察组在此基础上加用盐酸氟桂利嗪治疗,对比两组的疗效、眩晕缓解时间、平均住院时间及不良反应发生率。结果观察组治疗总有效率及眩晕缓解时间均优于对照组(P<0.05),观察组平均住院时间少于对照组(P<0.05),两组不良反应发生率对比差异无统计学意义(P>0.05)。结论盐酸氟桂利嗪和长春西汀注射液联合治疗眩晕综合征能提高疗效,迅速缓解眩晕症状,减少住院时间,且不良反应发生率低,值得临床推广使用。

Objective To observe the efficacy of flunarizine hydrochloride combined with vinpocetine injecta in the treatment of patients with vertigo syndrome. Methods One hundred and two patients with vertigo syndrome treated in our hospital were chosen as the research object from September 2014 to July 2015 and the patients were randomly divided into observation group and control group, 51 cases in each group. The control group was treated by vinpocetine hydrochloride inject, the observation group was given flunarizine hydrochloride on the basis treatment of control group. The efficacy of the treatment, remission time, average hospitalization days, rate of adverse reaction of the two groups were compared. Results The total effective rate of observation group was better than that of control group(P <0.05), and the average hospitalization time in observation group was shorter than that in control group(P <0.05), the incidence of adverse reactions in the two groups was not statistically significant(P >0.05). Conclusion Flunarizine hydrochloride combined with vinpocetine injecta are helpful to the patients with vertigo syndrome which can improve the curative effect, reduce the symptoms and the average hospitalization time, do not increase the incidence of adverse reactions. It is worthy of clinical application.