血清CA153联合乳腺B超在乳腺占位性疾病性质鉴别中的应用价值

Application value of serum CA153 combined with breast B-mode ultrasonography in the differential diagnosis of breast space occupying disease

目的分析血清糖类抗原153(CA153)联合乳腺B超在乳腺占位性疾病性质鉴别中的应用价值。方法对120例乳腺占位性疾病患者的临床资料进行回顾性分析,对比良性患者和恶性患者血清CA153水平及乳腺B超检查结果,分析血清CA153、乳腺B超及血清CA153联合乳腺B超对疾病性质的鉴别价值。结果本组患者中共有32例恶性患者。恶性患者血清CA153水平高于良性患者(P<0.05)。不同类型良性患者血清CA153水平无显著差异(P>0.05)。良性和恶性患者乳腺B超检查特征差异明显。血清CA153联合乳腺B超对乳腺占位性疾病性质鉴别诊断的特异度和准确度均高于单纯血清CA153、乳腺B超检查。结论血清CA153联合乳腺B超对乳腺占位性疾病性质鉴别诊断的价值较高。

Objective To study the application value of serum carbohydrate antigen 153(CA153) combined with Bmode ultrasonography in the differential diagnosis of breast space occupying disease. Methods The clinical data of 120 patients with breast space occupying disease were retrospectively analyzed. The serum CA153 levels and breast B-mode ultrasonography results were compared, and the differential diagnosis value of serum CA153, breast B-mode ultrasonography,serum CA153 combined with breast B-mode ultrasonography were analyzed in benign and malignant patients. Results There were 32 malignant patients in this group. The serum CA153 level of malignant patients was higher than that of benign patients(P<0.05). There were no significant differences among different types of benign patients(P>0.05). There were significant differences in B-mode ultrasonography between benign and malignant patients. The specificity and accuracy of serum CA153 combined with breast B-mode ultrasonography in differential diagnosis of breast space occupying disease were higher than those of serum CA153 and breast B-mode ultrasonography alone. Conclusion Serum CA153 combined with breast B-mode ultrasonography has a higher value in differential diagnosis of breast space occupying disease.