自身免疫性胰腺炎与胰腺癌的超声特点及临床表现比较

Comparison of ultrasonography characteristics and clinical manifestations between autoimmune pancreatitis and pancreatic cancer

目的研究自身免疫性胰腺炎(AIP)和胰腺癌的超声特点及临床表现。方法回顾性分析30例AIP患者(观察组)和30例胰腺癌患者(对照组)的临床资料,比较AIP和胰腺癌患者的超声特点和临床表现。结果两组患者的肿瘤病灶直径、腹胀、体重下降及糖尿病史发生率比较,差异均无统计学意义(P>0.05);两组患者的病变范围、腹痛评分及黄疸发生率比较,差异均具有统计学意义(P<0.05)。观察组胰腺体尾部萎缩、胰管阻塞性扩张、血管受累发生率显著低于对照组,胆总管厚壁性狭窄和胆管壁增厚发生率显著高于对照组(P<0.05)。结论 AIP患者病变以弥漫性为主,腹部疼痛和黄疸症状及超声检查均有助于鉴别诊断。

Objective To study the ultrasonographic and clinical manifestations of autoimmune pancreatitis(AIP) and pancreatic cancer. Methods The clinicopathological data of 30 AIP patients(observation group) and 30 pancreatic cancer patients(control group) were retrospectively analyzed. The ultrasonography characteristics and clinical manifestations of patients with AIP and pancreatic cancer were compared. Results There were no significant differences in tumor diameter,incidences of abdominal distention, weight loss and diabetes history between the two groups(P >0.05). There were significant differences in the range of lesions, abdominal pain scores and incidences of jaundice between the two groups(P<0.05). The incidences of pancreatic atrophy, obstructive dilatation of pancreatic bile duct and vascular involvement in the observation group were significantly lower than those in the control group, the incidences of choledochal thickening stenosis and bile duct wall thickening were significantly higher than those of the control group(P<0.05). Conclusion The lesions of AIP patients are mainly diffuse, the abdominal pain, jaundice symptoms and ultrasonography are helpful for differential diagnosis.