小剂量人血白蛋白联合呋塞米及甘露醇治疗对重度颅脑损伤患者血清BNP和NSE水平的影响被引量：3

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摘要目的探讨甘露醇联合不同药物治疗方案对重度颅内损伤后脑钠肽(BNP)及神经元特异性烯醇化酶(NSE)的影响。方法按照随机数字表法将204例重度颅内损伤患者分为接受联合甘露醇及呋塞米治疗的对照组及接受甘露醇、呋塞米及小剂量人血白蛋白治疗的研究组,每组102例。分别对比两组治疗前及治疗7.14d后BNP及NSE水平。结果两组治疗前,BNP及NSE水平比较,差异均无统计学意义(P>0.05),而治疗7d时两组BNP及NSE均升高,但研究组低于对照组;而在治疗14d时,两组BNP及NSE均较7d时显著下降,研究组仍低于对照组(P<0.05)。结论甘露醇、呋塞米及小剂量人血白蛋白在重度颅内损伤治疗中,可更为有效地降低患者血清BNP及NSE水平。

作者刘福增张亚雯孙孟雄杨帅孙斌徐志富王锡丽

机构地区解放军第二五一医院河北医科大学第三医院张家口市第一医院张家口市肺科医院

出处《医疗装备》 2016年第8期14-15,共2页 Medical Equipment

关键词重度颅内损伤人血白蛋白呋塞米脑钠肽神经元特异性烯醇化酶

分类号 R651.15 [医药卫生—外科学]

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