破布草化学成分研究

Studies on the chemical constituents from Stachys kouyangensis

利用多种色谱手段对产自于云南省富民县的破布草地上部分70%丙酮-水提取物的乙酸乙酯萃取部位进行化学成分研究,通过化合物波谱数据鉴定其结构,分别鉴定为:6-羟基-豆甾-4-烯-3-酮(1)、豆甾-4,22-二烯-3-酮(2)、β-谷甾醇(3)、S-(+)-去氢催吐萝芙木醇(4)、地芰普内酯(5)、植物醇(6)、安告佛醇(7)、反式咖啡酸(8)、丁香酸(9)、水杨酸(10)、十二酸(11).其中,化合物1,2,4,5和7为水苏属植物中首次报道,所有化合物均首次从破布草中分离得到.

To study the chemical constituents of Stachys kouyangensis(Vaniot)Dunn collected in Fumin County,Yunnan Province,70%acetone aqueous extract of the aerial parts of.S.kouyangensis were separated and purified by chromatography methods.As a result,eleven compounds were isolated and determined by spectroscopic analysis to be:6-hydroxystigmast-4-en-3-one(1),stigmast-4,22-dien-3-one(2),β-sitosterin(3),S-(+)-dehydrovomifoliol(4),loliolide(5),phytol(6),angophorol(7),trans-caffeic acid(8),syringic acid(9),salicylic acid(10),dodecanoic acid(11),respectively.All compounds were obtained from S.kouyangensis for the first time,and compounds 1,2,4,5,and 7 were the first isolates from the genus Stachys.