设计左旋糖酐——果糖的合成实验探索与综合改进

Design of synthesis experiment of levo-fructose and comprehensive improvement

开展物理化学综合性设计型实验教学改革,研究蔗糖转化实验,探索设计左旋糖酐(果糖)的合成实验研究.利用旋光仪测旋光度的方法监测溶液中蔗糖的浓度变化情况,从而测得其转化率及动力学规律.根据果糖和葡萄糖的钙离子络合物的性质差异实现纯化和有效分离、洗涤、干燥,获得要求的产品,并引入薄层色谱实现快速检测.建立起一项完整的实验教学项目,有效促进探究型实验教学发展,同时完善综合性设计型实验,进一步有效落实教学改革.

To carry out the comprehensive and disignating reform of the education of the physical chemistry experiments,and to explore the experimental conditions of the transformation reaction of sucrose into glucose and fructose,and to explore changes and variation of the synthesis experiment of the design of levulose-fructose,optical rotatory activity was used to monitor the change of sucrose and glucose and fructose concentration in the solution,then the conversion rate and kinetic law were measured out.According to the difference of the properties of the calcium ion complex of fructose and glucose,the purified and effective separation,washing and drying were achieved,and the required products were obtained,and the rapid detection was realized by the thin layer chromatography of silica gel.A complete experimental teaching project should be set up to promote the development of exploratively experimental teaching,so as to improve the comprehensive design experiment and carry out the teaching reform effectively.