碳纳米管-电沉积Co修饰电极在抗坏血酸存在下同时测定多巴胺和尿酸

Simultaneous Determination of Dopamine and Uric Acid at Electrodeposited Cobalt Oxide-carbon Nanotubes Modified Electrode in the Presence of Ascorbic Acid

采用滴涂法和循环伏安法(CV)将碳纳米管和Co修饰到玻碳电极表面,得到碳纳米管-电沉积Co修饰电极,研究了多巴胺(DA)、尿酸(UA)在碳纳米管-电沉积Co修饰电极上的电化学响应.结果表明,在0.1mol/L磷酸缓冲液(pH=6)中,DA、UA在该电极上均显示出良好的电化学响应,碳纳米管-电沉积Co修饰的玻碳电极能够将DA和UA的氧化峰电位明显分开,两者峰电位差为124mV,并且可以在抗坏血酸(AA)存在下同时测定DA和UA.该修饰电极选择性好、稳定性高,可以实现AA存在下DA和UA共存时两种物质的定量检测.

Cobalt oxide was modified onto the surface of carbon nanotubes modified GCE by cyclic voltammetrical method and the electrochemical response of DA and UA were investigated on the proposed electrode.It indicates that DA and UA shows favorable electrochemical response in pH 6PBS respectively,and the electro-separation of peak for the electro-oxidation of DA and UA with peak separation of 124 mV,which can be used to simultaneous determination of DA and UA.The results also show that the simultaneous determination of DA and UA can also be processed in the presence of ascorbic acid with favorable reproduction and accuracy and has been used to determinate DA and UA in simulated and real samples with satisfactory results.