槟榔等四种兴奋剂不同服用量的兴奋作用比较研究

Comparative Study of Excitatory Effect of Different Consumption of Four Kinds of Stimulant like Areca Catechu

目的:通过观察口味王和成天下槟榔(A组)、口味王精制青果食用槟榔(B组)与即溶咖啡饮品(C组)、红牛维生素功能饮料(D组)服用不同剂量对小鼠自主活动次数(Y值)的影响,寻找槟榔等四种样品兴奋作用最佳服用量,比较四种产品兴奋作用的特性和差别,为广大消费者科学正确地把握槟榔等四种产品服用量提供依据。方法:小鼠100只,雄雌各半,随机分成5组,每组20只,分别为口味王和成天下槟榔(A组)、口味王精制青果食用槟榔(B组)、即溶咖啡饮品(C组)、红牛维生素功能饮料(D组)、蒸馏水(E组),再将每组20只小鼠分为低、高服用量两个小组,总计10个小组,每小组单次灌胃给予相应受试物,给予受试物后每隔5min测定一次Y值,连续测定60min内Y值。建立Y值经时变化的数学模型,求出兴奋作用速度及强度参数,采用95%可信区间重叠法比较四种产品不同服用量兴奋作用速度及强度差别。结果:低服用量兴奋作用由强到弱:口味王精制青果食用槟榔≈即溶咖啡饮品>口味王和成天下槟榔>红牛维生素功能饮料>蒸馏水;低服用量兴奋作用速度由快到慢:口味王精制青果食用槟榔≈口味王和成天下槟榔≈红牛维生素功能饮料>即溶咖啡饮品>蒸馏水;而高服用量兴奋作用由强到弱:口味王精制青果槟榔>红牛维生素功能饮料≈即溶咖啡饮品>口味王和成天下槟榔>蒸馏水;高服用量兴奋作用由快到慢:口味王和成天下槟榔>即溶咖啡饮品>红牛维生素功能饮料>口味王精制青果槟榔>蒸馏水。口味王和成天下槟榔低服用量兴奋作用优于高服用量;即溶咖啡饮品高服用量兴奋作用优于低服用量;口味王精制青果槟榔、红牛维生素功能饮料兴奋作用均与低、高服用量兴奋作用相同。结论:口味王精制青果槟榔高、低服用量兴奋作用强弱及速度皆居首位;其次是高、低服用量的即溶咖啡饮品;再次是高服用量的红牛维生素功能饮料和低服用量的口味王和成天下槟榔。

Objective:To investigate the effects of different consumption of Areca Catechu of Hechentianxia of the King of Taste(Group A),Edible Areca Catechu of Jinzhiqingguo of the King of Taste(Group B),Instant Coffee of Beverage(Group C),Red Bull Vitamin Functional Beverages(Group D)on the mouse's independent active number of times(Values Y),find out the optimum consumption of the excitatory effect of four kinds of samples like Areca Catechu,compare the characteristics and difference of the excitatory effect of four kinds of products,provide the basis for consumers to properly handle the consumption of four kinds of samples.Methods:100mices which were composed of male and female in equal were divided at random into five supergroups,Hechentianxia of the King of Taste(supergroup A),Jinzhiqingguo of the King of Taste(supergroup B),Instant Coffee of Beverage(supergroup C),Red Bull Vitamin Functional Beverages(supergroup D),Distilled water(supergroup E),respectively.each supergroups(20mices)was divided into two subgroups,low consumption subgroups and high consumption subgroups respectively,about 10subgroups in total.Each subgroup was given corresponding test substances through intragastric administration,Value Y was continuous measured every other five minutes after intragastric administration test substances in 60minutes.Mathematical Model of Value Y changed with time was built,the parameters of speed and strength of excitatory effect were founded,the distinction of speed and strength of excitatory effect of the different consumption of four kinds of samples was compared through 95%Confidence Interval Overlap Method.Results:Excitatory effect of low consumption from strong to weak was:Jinzhiqingguo of the King of Taste≈Instant Coffee of Beverage>Hechentianxia of the King of Taste>Red Bull Vitamin Functional Beverages>Distilled water,Speed of excitatory effect of low consumption from fast to slow was:Jinzhiqingguo of the King of Taste≈Hechentianxia of the King of Taste≈Red Bull Vitamin Functional Beverages>Instant Coffee of Beverage>Distilled water,excitatory effect of high consumption from strong to weak was:Jinzhiqingguo of the King of Taste>Red Bull Vitamin Functional Beverages≈Instant Coffee of Beverage>Hechentianxia of the King of Taste>Distilled water,Speed of excitatory effect of high consumption from fast to slow was:Hechentianxia of the King of Taste>Instant Coffee of Beverage>Red Bull Vitamin Functional Beverages>Jinzhiqingguo of the King of Taste>Distilled water,excitatory effect of low consumption of Hechentianxia of the King of Taste was better than high consumption,excitatory effect of high consumption of Instant Coffee of Beverage was better than low consumption,excitatory effect of low consumption of subgroups Jinzhiqingguo of the King of Taste,Red Bull Vitamin Functional Beverages,was equal to high consumption.Conclusion:excitatory effect of both low and high consumption of Jinzhiqingguo of the King of Taste were topped the list,both low and high consumption of the Instant Coffee of Beverage were on the second,high consumption of Red Bull Vitamin Functional Beverages and low consumption of Hechentianxia of the King of Taste were on the third.