硫酸软骨素生产工艺现状与解析

Production Technique of Chondroitin Sulfate: Current Status and Analysis

硫酸软骨素(Chondroitin sulfate,CS)是我国一种重要的出口原料药,有多种生产工艺。文章通过对CS不同的生产工艺进行介绍与解析,期望促进CS生产工艺的改进,使生产企业获得更高的效益。查阅近年来国内外发表的相关文献,结合实际的工业生产状况,对其进行归纳、分析与总结。文章综述了CS的生产工艺现状,并进行了深度分析,对酶技术、膜技术、微生物发酵技术等作了较为详细的介绍。从本质上理解CS的生产工艺,深入研究每种方法和技术的原理及使用条件,有利于CS生产工艺的改进及创新,进一步提升产品质量和企业效益。

Chondroitin sulfate( CS) is an important exportone of bulk drugs in China,which has diverse production techniques. In the present paper,different techniques of CS product have been introduced and analyzed,in order to get improvement,and help CS enterprises to obtain higher benefit. More related papers published at home and abroad,combined with actual situation of industrial production were organized,analyzed,and summarized in this paper. Here is reviewed the current status of CS production techniques,and is made a further analysis. The techniques used in the production such as enzymatic,membranes and microbial ones have been introduced. Comprehension of the CS production technique in essence and in-depth study of the theory and conditions of each technique will be good to gain improvement and innovation,further enhancing product quality and enterprise benefit.