婴幼儿斯坦利沙门氏菌院内感染病例病原学调查分析

Investigation on pathogenic features of nosocomial infections of Salmonella stanley cases in infants

目的对平顶山市婴幼儿斯坦利沙门氏菌院内感染病例进行病原学分析,为科学防控提供依据。方法采集外环境标本和可疑菌株进行斯坦利沙门氏菌检测,对阳性菌株进行血清分型和耐药性试验。结果共发现斯坦利沙门氏菌感染病例14例,均为1岁以下婴幼儿,发病时间集中于4月。分离斯坦利沙门氏菌阳性菌株8株,耐药谱一致,均对阿莫西林、头孢噻肟、头孢吡肟等8种抗生素耐药。结论病例间存在院内感染,应加强沙门氏菌病原学监测,合理规范使用抗菌药物,加强消毒效果监测和管理。

Objective To analyze the pathogenic features of Salmonella stanley hospital infection infant cases in Pingdingshan,so as to provide a reference for scientific control and prevention. Methods External environment specimens and suspicious strains were collected for stanley detection,and the positive strains were tested for serotyping and drug resistance. Results A total of 14 Salmonella stanley cases were found,all of which were infants under 1 year of age. The onset time was concentrated in April. Eight strains of stanley positive strains were isolated,and the drug resistance spectrum was consistent. They were resistant to 8 kinds of antibiotics,such as amoxicillin,cefotaxime,cefepime and so on. Conclusion There are nosocomial infections between cases,and the pathogen monitoring of Salmonella should be strengthened. The use of antibiotics should be rationally regulated,and the monitoring and management of disinfection effects should be enhanced.