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血尿酸水平与慢性心力衰竭的关系及临床意义

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摘要 目的:探讨慢性心力衰竭患者血清尿酸水平的变化及临床意义。方法:回顾性分析我院冠心病伴慢性心力衰竭患者96例,观察尿酸水平与心功能的关系,并与同期冠心病不伴心力衰竭的96例患者作比较分析,随访1年内心血管事件发生情况。结果:观察组血清尿酸水平(378.3±92.7)μmol/L,对照组血清尿酸水平(349.2±81.5)μmol/L,两组比较,差异有统计学意义(t=9.27,P=0.01)。NYHAⅡ级、NYHAⅢ级、NYHAⅣ级组高尿酸血症发生为13例、19例、26例,差异有显著性(χ2分别为5.20、7.24,P分别为0.03、0.01)。随访1年,冠心病伴高尿酸血症组发生心血管事件37例(37/58),冠心病不伴高尿酸血症发生心血管事件7例(7/38),两组比较差异有统计学意义(χ2=19.03,P=0.00)。结论:尿酸是慢性心力衰竭患者心血管事件的预测因子,监测血清尿酸水平变化对患者的临床治疗有指导意义。
出处 《医学理论与实践》 2014年第15期1996-1997,共2页 The Journal of Medical Theory and Practice
关键词 心力衰竭 尿酸
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