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普伐他汀钠联合非诺贝特对老年高脂血症的治疗

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摘要 目的:探讨普伐他汀钠联合非诺贝特对老年混合型高脂血症的治疗。方法:分析研究510例明确诊断混合型高脂血症的老年患者,对比服用普伐他汀钠片联合非诺贝特胶囊与单独服用普伐他汀钠片后6个月后的甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL),同时监测服药6个月后转氨酶及心肌酶的变化。结果:(1)单独使用普伐他汀钠片降脂患者组,能够降低TG、TC、LDL水平(P<0.05),差别有统计学意义。(2)使用普伐他汀钠联合非诺贝特治疗降脂患者组,能够明显降低TG、TC、LDL水平,达标率高于单独服用普伐他汀钠患者(P<0.05),差别有统计学意义。(3)无论单独服用普伐他汀钠或服用普伐他汀钠联合非诺贝特,与对照组相比,转氨酶及心肌酶均未见异常。结论:普伐他汀钠联合非诺贝特较单独服用普伐他汀钠能够更好地降低老年混合型高脂血症的血脂水平,并且比较安全。
作者 李爱敏
出处 《医学理论与实践》 2014年第15期2010-2011,共2页 The Journal of Medical Theory and Practice
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