老年住院患者rT_3水平与患者营养代谢状态的关系

The Levels of rT_3 Related About the Nutritional Status in Aged Inpatients

目的:了解老年住院人群rT3水平与患者住院期间营养状态之间的关系。方法:收集2011-2013年在我院老年病科进行血甲状腺功能测定的老年患者共168例,采集一般临床资料如既往史、服药史、血甲状腺功能测定结果及其他生化检查数据,详细记录血清促甲状腺激素(TSH)、游离甲状腺素(FT3、FT4)、甲状腺过氧化物酶抗体(TPOAb)和甲状腺球蛋白抗体(TgAb)、rT3、血清白蛋白(ALB)和总胆固醇(CHO)值。根据入院时rT3升高与否将患者分成两组:rT3升高组与rT3正常组。比较rT3升高组与rT3正常组血生化及其他甲状腺功能指标差异。结果:(1)rT3升高组患者血清白蛋白、胆固醇水平、FT3水平均显著低于rT3正常组患者(P<0.05);(2)rT3升高组患者分别按血浆白蛋白及胆固醇水平分2个亚组,各亚组间的rT3水平有统计学差异(P<0.05)。结论:老年住院人群rT3水平与患者住院期间血浆白蛋白及胆固醇水平有关,老年患者rT3水平可间接反映患者营养状态。

Objective:To analyze the correlation of rT3 with biochemical parameters.Methods:168inpatients aged 70~93in our geriatric department were consecutively enrolled between 2011 and 2013.General conditions,thyroid parameters and biochemical datas were recorded detailedly.Severity of the illness was also evaluated when the patients were admitted in Concentrations of serum thyroid stimulating hormone(TSH),free thyroid hormone(FT3and FT4),thyroid peroxidase antibodies(TPOAb),thyroid globulin antibody(TgAb),rT3,albumin and cholesterol were inspected respectively.Patients were devided into two groups based on the baseline rT3:Group of elevated rT3(without the interference of amiodarone)and Group of normal rT3.We tried to compare the differences of biochemical parameters between the two groups.Results:Patients in Group of elevated rT3 had lower levels of serum albumin,cholesterol and FT3 than those in Group of normal rT3(P<0.05).Even those in Group of elevated rT3 had a distinct rT3 with different levels of serum albumin and cholesterol(P<0.05).Conclusion:Elevated rT3 usually observed in patients with lower levels of serum albumin,cholesterol.So rT3 might be reflect patients’ nutritional status indirectly and should be monitored in aged inpatients,especially with serious illnesses.