一贯煎加减治疗肝硬化腹水的疗效观察

Observation on the Therapeutic Effect of Consistent Decoction plus Subtractive on Ascites Due to Cirrhosis

目的探讨一贯煎加减治疗肝硬化腹水的临床疗效。方法选择2014年9月～2017年10月我院门诊和住院治疗的肝硬化腹水患者65例,随机分为治疗组(35例)和对照组(30例)。对照组患者在西药常规治疗基础上用六味地黄丸治疗,治疗组在西药常规治疗基础上以一贯煎为主方,通过辩证加减治疗。2个疗程后观察患者的临床疗效及血清TBiL、ALT、ALB水平差异。结果治疗组的总有效率为94.29%,高于对照组的76.67%,差异有统计学意义(P<0.05);治疗组患者血清TBiL、ALT、ALB水平改善均优于对照组,差异有统计学意义(P<0.05)。结论一贯煎加减治疗肝硬化腹水可以改善患者患者肝功能指标,提高临床疗效,值得临床借鉴。

Objective To investigate the clinical efficacy of consistent decoction plus subtractive in the treatment of ascites due to cirrhosis.Methods 65 patients with cirrhosis and ascites from our hospital from September 2014 to October 2017 were randomly divided into treatment group(35 cases) and control group(30 cases). The patients in the control group were treated with Liuwei Dihuang Pill on the basis of conventional western medicine treatment. The treatment group was treated with traditional decoction on the basis of conventional western medicine, and was treated by dialectical addition and subtraction. After 2 courses of treatment, the clinical efficacy and serum levels of TBiL, ALT and ALB were observed.Results The total effective rate of the treatment group was 94.29%, which was higher than that of the control group 76.67%,the difference was statistically significant(P <0.05). The serum levels of TBiL, ALT and ALB in the treatment group were better than those in the control group,the difference was statistically significant(P<0.05).Conclusion Consistent decoction plus subtractive and treatment of ascites due to cirrhosis can improve the liver function of patients and improve clinical efficacy, which is worthy of clinical reference.