影像技术和分子检测技术在阿尔茨海默病诊断中的应用研究进展

Advances in the application of imaging and molecular detection technology in the diagnosis of Alzheimers disease

阿尔茨海默病(Alzheimer disease,AD)是以进行性发展的神经系统退行性变为特征的病变,它给患者、家庭和社会造成了很大的负担,因此亟待寻找早期诊治AD的方法。目前,神经影像新技术和分子检测技术发展迅速,如对海马、灰质等的测量与基因检测等,都对AD的早期诊断有非常重要的价值。本文将结合国内外关于影像技术和分子检测技术在AD早期诊断中的应用进展作一综述,为AD的预防管理提供新思路。

Alzheimers disease(AD)is a disease characterized by progressive neurodegeneration of the nervous system,which imposes a great burden on patients,families and society. Therefore,it is urgent to find a way to diagnose AD early. At present,the rapid development of new neuroimaging technology and molecular detection technology,such as the measurement of hippocampal,gray matter and gene detection,are of great importance to the early diagnosis of AD. In this paper, the application of imaging technology and molecular detection technology in the early diagnosis of AD at home and abroad will be reviewed,to provide new ideas for the prevention and management of AD.