核磁共振成像联合脑脊液分析鉴别诊断中枢神经系统感染的价值观察

Value of magnetic resonance imaging combined with cerebrospinal fluid analysis in differential diagnosis of central nervous system infection

目的:探讨核磁共振成像(MRI)联合脑脊液分析鉴别诊断中枢神经系统感染的价值。方法:选取2016年2月—2017年6月在我院就诊的中枢神经系统感染者30例为观察组,并选取同期因头痛就诊的患者20例为对照组,均行核磁共振成像联合脑脊液检查,比较两组MRI诊断结果及脑脊液相关指标。结果:观察组MRI检查阳性率明显高于对照组,差异有统计学意义(P<0.05);结核性脑膜炎及化脓性脑膜炎乳酸(LA)浓度明显高于病毒性脑膜炎,差异有统计学意义(P<0.05);化脓性脑膜炎肌酸激酶(CK)浓度明显高于结核性脑膜炎及病毒性脑膜炎,差异有统计学意义(P<0.05);结核性脑膜炎乳酸脱氢酶(LDH)水平明显高于化脓性脑膜炎及病毒性脑膜炎,差异有统计学意义(P<0.05)。结论:核磁共振成像联合脑脊液分析可有效鉴别中枢神经系统感染类型,为治疗方案确定提供依据。

Objective To investigate the value of magnetic resonance imaging(MRI) combined with cerebrospinal fluid(CSF) analysis in differential diagnosis of central nervous system infection(CNSI). Methods 30 CNSI patients in our hospital from February 2016 to June 2017 were selected as observation group, and 20 patients with headache were selected as control group at the same time. All patients were given MRI and CSF examination. The MRI results and CSF indexes were compared between the two groups. Results The positive detection rate of MRI in observation group was higher than that in control group(P<0.05); The lactic acid(LA) concentration of tuberculous meningitis and purulent meningitis was higher than that of viral meningitis(P<0.05); The creatine kinase(CK) concentration of purulent meningitis was higher than that of tuberculous meningitis and viral meningitis(P<0.05); The lactate dehydrogenase(LDH) level of purulent meningitis was higher than that of purulent meningitis and viral meningitis(P<0.05). Conclusion MRI combined with CSF analysis in differential diagnosis of CNSI is effective, it can provide basis for determining treatment regimen.