复方阿嗪米特联合PPI和胃动力药治疗胆汁反流性胃炎的疗效观察

Efficacy of compound azinomide combined with PPI and gastric motility in the treatment of bile reflux gastritis

目的:对胆汁反流性胃炎患者应用复方阿嗪米特联合PPI及胃动力药进行治疗的疗效进行探究。方法:此次研究对象为自2016年10月-2017年7月间在我院接受胆汁反流性胃炎治疗的患者,随机将患者分为对照组和观察组,各60例,对照组患服用奥美拉唑肠溶片及莫沙必利分散片,观察组患者用药同对照组,同时加服复方阿嗪米特肠溶片。结果:用药前后两组患者临床症状均得到显著改善,差异显著(P<0.05),观察组患者积分下降程度明显高于对照组,差异显著(P<0.05)。用药前后两组患者胆汁反流情况均得到显著改善,差异显著(P<0.05),观察组患者胆汁反流次数以及反流时间减少程度明显高于对照组,差异显著(P<0.05)。结论:对胆汁反流性胃炎患者应用复方阿嗪米特联合PPI及胃动力药可有效改善患者病情。

Objective To explore the efficacy of compound azinomide combined with PPI and gastric motility in patients with bile reflux gastritis. Methods The subjects were treated with bile reflux gastritis from October 2016 to July 2017. The patients were randomly divided into control group and observation group. Sixty patients were treated with control group Omeprazole enteric-coated tablets and mosapride tablets, the observation group of patients with the same control group,while the addition of compound azazepine enteric-coated tablets. Results The clinical symptoms of the two groups were significantly improved before and after treatment(P <0.05). The score of the observation group was significantly higher than that of the control group(P <0.05).(P <0.05). The degree of bile reflux and the degree of reflux were significantly higher in the observation group than in the control group(P <0.05), and the difference was significant(P <0.05). Conclusion The combination of compound azinomide combined with PPI and gastric motility can improve the condition of patients with bile reflux gastritis.