全甲状腺切除术与次全切术治疗分化型甲状腺癌的临床疗效比较

Comparison of the clinical curative effect of total thyroidectomy and subtotal resection in the treatment of differentiated thyroid carcinoma

目的:比较全甲状腺切除术与次全切术治疗分化型甲状腺癌的临床疗效。方法:选择我院收治的114例分化型甲状腺癌患者,所有患者均经手术病理结果确诊,按照手术方式的不同将患者分为全甲状腺切除术治疗组(全切组)和甲状腺次全切术治疗组(次全切组),每组57例,术后对患者进行随访,对近期疗效和远期疗效进行评价。结果:两组患者术后临床症状均得到了显著改善,全切组患者术后并发症发生率高于对照组,术后低血钙及暂时性喉返神经麻痹发生率组间差异有统计学意义(P<0.05);全切组患者术后局部复发及远处转移率明显低于次全切组患者,组间差异有统计学意义(P<0.05)。结论:全甲状腺切除术与次全切术治疗分化型甲状腺癌的近期疗效相当,次全切术后并发症发生率较低,全切术后患者的远期疗效较好,应根据患者的具体情况选择合理的术式。

Objective To compare the clinical efficacy of total thyroidectomy and subtotal resection in the treatment of differentiated thyroid carcinoma. Methods 114 patients with differentiated thyroid cancer patients in our hospital, all patients were confirmed by surgery and pathology results, according to different surgical methods were divided into treatment group(total thyroidectomy resection group) and subtotal resection group(subtotal resection group), each group of 57 patients after operation the patients were followed up, to evaluate the short-term and long-term efficacy. Results Two groups of patients with clinical symptoms were significantly improved, total resection rate of postoperative complications was higher than the control group, postoperative hypocalcemia and temporary recurrent laryngeal nerve palsy between group differences in incidence was statistically significant(P<0.05); all groups of patients with postoperative local recurrence and distant metastasis rate below the subtotal resection group, there was significant difference between the groups(P<0.05). Conclusion The curative effect of total thyroidectomy and a subtotal resection in the treatment of differentiated thyroid carcinoma, subtotal resection and low rate of postoperative complications, good long-term curative effect in patients after hysterectomy, surgery should be selected according to the specific situation of the patients.