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血清肿瘤标志物联合CT检测在非小细胞肺癌诊断中的价值分析 被引量:6

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摘要 目的:分析血清肿瘤标志物联合CT检测在非小细胞肺癌诊断中的诊断价值。方法:在2016年2月—2017年3月收集非小细胞肺癌患者100例,同时选取肺良性病变患者100例。两组患者均接受血清肿瘤标志物联合CT检测,探讨诊断价值。结果:非小细胞肺癌患者血清CEA、CA125、CYFRA21-1的测定值及阳性率均高于肺良性病变患者,三项数据差异均显著,具备统计学意义(P<0.05)。CEA、CA125、CYFRA21-1联合检测的敏感性与特异性分比为96.1%与86.6%。结论:CT联合血清肿瘤标志物检测可显著提高非小细胞肺癌患者的诊断效果,值得临床推广应用。
出处 《影像研究与医学应用》 2018年第7期130-131,共2页 Journal of Imaging Research and Medical Applications
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  • 1赫捷,陈万青.2012中国肿瘤登记年报[M].北京:军事医学科学出版社,2012:12-25.
  • 2Kim H,Park N,Chung H,et al. Serum CA-125 level after 6 cy- cles of primary adjuvant chemotherapy is a useful prognostic fac- tor for complete responders' survival in patients with advanced epithelial ovarian cancer[ J]. Onkologie, 2008, 31:315-320.
  • 3Shitrit D,Zingerman B, Shitrit A B G, et al. Diagnostic value of CYFRA 21-1 ,CEA, CA 19-9,CA 15-3,and CA 125 assays inpleural effusions : analysis of 116 cases and review of the litera- ture[J]. The Oncologist, 2005, 10:501-507.
  • 4Ando S, Kimura H, Iwai N, et al. Optimal combination of seven tumour markers in prediction of advanced stage at first examina- tion of patiems with non-small cell lung cancer[ J]. Anticancer research, 2000, 21:3085-3092.
  • 5Molina R,Filella X,Auge J M,et al. Tumor markers (CEA,CA 125 ,CYFRA 21-1, SCC and NSE ) in patients with non-small cell lung cancer as an aid in histological diagnosis and prognosis [J]. Tumor biology, 2003, 24:209-218.
  • 6Li X, Asmitananda T, Gao L, et al. Biomarkers in the lung cancer diagnosis: a clinical perspective [J]. Neoplasma, 2012,59 (5) : 500-507.
  • 7Ferraro S, Braga F, Lanzoni M, et al. Serum human epidid- ymis protein 4 vs carbohydrate antigen 125 for ovarian cancer diagnosis: a systematic review[J]. J Clin Pathol, 2013,66 (4) : 273-281.
  • 8Drescher CW, Shah C, Thorpe J, et al; Longitudinal screening algorithm that incorporates change over time in CA125 levels identifies ovarian cancer earlier than a single-threshold rule [J]. J Clin Oncol, 2013,31 (3) : 387- 392.
  • 9Azzam AZ, Hashad DI,Kamel NA. Evaluation of HE4 as an extrabiomarker to CA125 to improve detection of ovar- ian carcinoma:is it time for a step forward [J]. Arch Gy- necol Obstet,2013,288(1) :167-172.
  • 10Chang CC,Chiu NF,Lin DS,et al. High sensitivity detec- tion of carbohydrate antigen 15-3 using a gold/znc oxide thin film surface plasmon resonance based biosensor[J]. Anal Chem,2010,82(4) :1207-1212.

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