过敏性鼻炎的治疗进展

The treatment of allergic rhinitis

过敏性鼻炎即变应性鼻炎,是指特应性个体接触变应原后,主要由IgE介导的介质(主要是组胺)释放,并有多种免疫活性细胞和细胞因子等参与的鼻黏膜非感染性炎性疾病。国际上治疗过敏性鼻炎的方案主要有远离过敏源、药物疗法、免疫疗法、物理疗法、手术疗法、替代疗法等。各种疗法均有各自优缺点。目前还未发现根治的方法,临床上需根据患者的症状对症治疗,提高治疗效果,降低不良反应发生次数,保证用药安全性。本文就近年有关治疗过敏性鼻炎的临床研究概况综述如下。

Allergic rhinitis or allergic rhinitis, is refers to the atopic individuals after exposure to allergens, mainly mediated by IgE medium(mainly histamine) release, and there are a variety of immune active cells and cytokines involved in the nasal mucosa of noninfectious inflammatory disease. The international treatment of allergic rhinitis mainly includes remote allergy source, drug therapy, immunotherapy, physical therapy, surgical therapy, and alternative therapy. Various treatments have their own advantages and disadvantages. At present, no radical cure is found. Clinically, it is necessary to treat the symptoms according to the symptoms of the patients, improve the therapeutic effect, reduce the number of adverse reactions, and ensure the safety of the drug. This article reviews the recent clinical studies on the treatment of allergic rhinitis as follows.