小细胞肺癌影像学参数与手术预后的关系研究

Study on the relationship between imaging parameters and prognosis of small cell lung cancer

目的:探讨周围型Ⅰ期小细胞肺癌CT影像学参数与手术预后的相关性研究。方法:分析整理我院2000年—2015年确诊周围型Ⅰ期小细胞肺癌并接受手术治疗的85例患者进行CT图像分析并观察SCLC患者经不同术氏切除后生存期比较。结果:(1)肺段切除或楔形切除术17例,生存期中位数17个月;(2)肺叶切除术33例,生存期中位数28个月;(3)袖氏肺叶切除术25例,生存期中位数26个月;(4)全肺切除术10例,生存期中位数12个月。不同术氏的SCLC患者生存期之间比较,肺叶切除术及袖氏肺叶切除术后生存期均大于肺段切除或楔形切除术、全肺切除术患者。差异有统计学意义(P <0.05)。结论:CT在周围型Ⅰ期小细胞肺癌中具有较高诊断价值,并指导临床通过不同术氏切除,提高患者生存期,具有重要临床意义。

Objective To explore the correlation between the imaging features of CT and prognosis after operation in peripheral lung cancer I phase. Methods We reviewed the CT findings and clinical characteristics of 85 patient confirmed by peripheral lung cancer I phase in our hospital from 2000 to 2015. Results The outcomes as follow:(1) segment or wedge resection of lung in 17 cases;the median survival time for 17 months;(2) lobectomy of lung in 33 cases,the median survival time for 28 months;(3) sleeve lobectomy of lung in 25 cases,the median survival time for 26 months;(4) total pneumonectomy in 10 cases;the median survival time for 12 months.Different type of surgery has shows a difference outcomes.Lobectomy and sleeve lobectomy of lung has a better median survival time than segment resection and total pneumonectomy.The result is significant differences(P<0.05) Conclusion CT has a high value in diagnosis and treatment of localized small cell lung cancer, then to guide operative principle and improve prognosis.