超声造影对甲状腺良恶性结节的鉴别诊断价值

The Value of Contrast-Enhanced Ultrasound in Differential Diagnostic of Benign and Malignant Thyroid Nodules

目的:探讨超声造影在鉴别诊断甲状腺良恶性结节中的价值。方法:对常规超声难以明确定性诊断的158个甲状腺实性结节行超声造影检查,对照手术病理结果,回顾性动态观察结节的超声造影灌注过程,分析超声造影各项指标包结节括增强方式、增强强度、造影剂是否均匀分布、边界是否清晰以及造影时病灶范围较二维是否扩大。结果:甲状腺良恶性结节增强方式、增强强度、造影剂分布是否均匀、边界是否清晰以及造影时病灶范围较二维是否扩大差异均有统计学意义(P <0.05)。甲状腺恶性结节多表现为不均匀增强(95.93%)、低增强(84.55%)、造影后边界不清(82.93%)。少数恶性结节造影后范围较二维扩大,所有良性结节造影后范围无明显扩大。结论:超声造影在甲状腺良恶性结节的鉴别诊断具有重要价值。

Objective To investigate the diagnostic value of contrast-enhanced ultrasound in benign and malignant thyroid nodules. Methods 158 thyroid nodules detected by conventional ultrasonography were underwent contrast-enhanced ultrasound. All the nodules were confirmed by pathology. The enhancement patterns of nodules were evaluated in comparison with adjacent thyroid. Evaluation criterions were as follows : Process o f enhancement,degree of enhancement,homogeneity of enhancement,boundary of the enhanced lesions,range of the enhanced lesions. Results Contrast-enhanced patterns were significantly different between benign and malignant thyroid nodules( P <0.05), Malignant thyroid nodules were characterized by inhomogeneously(95.93%),low enhancement(84.55%)and unclear boundary(82.93%). A few malignant nodules were enlarged after while all benign nodules showed no significant enlargement after contrast-enhanced ultrasound. Conclusion Contrast-enhanced ultrasound has important value in differential diagnosis of benign and malignant thyroid nodules.