热重法分析卤化丁基橡胶塞的成分

Analysis of the Components of Halogenated Butyl Rubber Stopper by Thermal Gravimetric Analysis Method

目的分析卤化丁基胶塞的组成。方法采用热重(TGA)技术,分析卤化胶塞中水分、挥发性物质、橡胶、炭黑、灰分等信息。结果通过图谱比较,能识别配方中含碳酸钙的胶塞,TGA法能对代替法定标准检验灰分含量。结论该方法可用于评价胶塞配方的一致性,工艺的稳定性,为研究药物胶塞的选择奠定了基础。

Objective The composition of halogenated butyl rubber stoppers was analyzed. Methods Bythermogravimetric analysis,volatile matter, rubber, carbon black, ash and other information in halogenated rubber stopper were analyzed. Results Through the atlas comparison, plug containing calcium carbonate in the formulation was recognized.TGA method could replace the legal standard of inspection to detect ash content. Conclusion This method can be used to evaluate the consistency of the rubber plug formulation and the stability of the process, thus laying the foundation for choosing drug plug.