泮托拉唑和奥美拉唑治疗胃溃疡的疗效对比观察

Comparison on Effects of Pantoprazole and Omeprazole in Treating Gastric Ulcer

目的观察泮托拉唑和奥美拉唑治疗胃溃疡的临床疗效。方法将156例胃溃疡患者随机均分为观察组和对照组,各78例。对照组采用奥美拉唑治疗,观察组采用泮托拉唑治疗,观察两组临床疗效。结果观察组总有效率和对照组比较,差异无统计学意义(P>0.05)。观察组幽门螺旋杆菌根除率、胃溃疡复发率和治疗费用均低于对照组(P<0.05)。结论泮托拉唑与奥美拉唑治疗胃溃疡的临床疗效相当,但根除幽门螺旋杆菌效果优于奥美拉唑,且治疗后复发率低,治疗费用少,值得临床推广。

Objective To observe the clinical effect of pantoprazole and omeprazole in treating gastric ulcer.Methods One hundred and fifty-six patients with gastric ulcer admitted to our hospital were randomly divided into the observation group and the control group,78 cases in each group.The control group adopted the omeprazole for treatment,while the observation group used the pantoprazole treatment.The clinical therapeutic effects of the two groups were observed.Results The total effective rate of the observation group was similar to that of the control group,after statistics analysis,there was no statistically significant difference(P > 0.05).The helicobacter pylori eradication rate in the observation group was higher than that in the control group,the gastric ulcer recurrence rate and treatment costs in the observation group were lower than those in the control group,after statistics analysis and comparison,the difference between the two groups was statistically significant(P < 0.05).Conclusion Using pantoprazole for treating gastric ulcer has the same clinical effect as omeprazole,but its effect for eradicating helicobacter pylori is better than omeprazole',with low relapse rate after treatment and low treatment cost,which is worthy of clinical promotion.