经皮球囊成形术与选择性支架置入术用于下肢动脉严重狭窄疗效比较

Efficacy Comparison of Percutaneous Balloon and Selective Stent Implantation in Treating Severe Lower Limb Arteries Stenosis

目的探讨下肢动脉严重狭窄患者经皮球囊成形术或选择性支架置入术治疗的近中期疗效及安全性。方法选取2012年1月至2013年12月收治的下肢慢性缺血或严重间歇性跛行患者140例。其中39例行经皮球囊成形术(A组),101例行选择性支架置入术(B组)。结果治疗后6,12个月随访结果显示,两组髂动脉和股动脉的再狭窄及所有病变的发生率相比,差异均无统计学意义(P>0.05);与B组相比,A组的6 min最大步行距离及踝肱收缩压比均明显较小(P<0.01)。结论经皮介入在下肢动脉阻塞的治疗中的安全性较强。但中期疗效表明,两组的再狭窄的发生率无显著差异,而B组的6 min最大步行距离以及踝肱收缩压比明显优于A组。

Objective To evaluate the short and medium term efficacy and safety of percutaneous balloon and selective stent implan-tation in treating severe lower limb arteries stenosis. Methods 140 cases severe lower limb chronic ischemia or intermittent claudication from January 2012 to December 2013 in the hospital were selected. 39 cases received percutaneous balloon ( group A ) , 101 cases under-went selective stenting ( group B ) . Results 6,12 months follow-up showed that the iliac femoral artery and artery restenosis and the incidence of all lesions in the two groups had no statistically significant ( P > 0. 05 );compared with group B, the 6 min walking dis-tance and the ratio of ankle brachial contraction in the group A had statistically significant difference ( P < 0. 01 ) . Conclusion The percutaneous balloon in treating severe lower extremity arteries stenosis is safer than selective stenting. Medium term efficacy indicates the restenosis rate of the two groups has no significant difference, but the 6 min walking distance and the ratio of ankle brachial con-traction in the group B is obviously better than the group A.