正交试验法优化口腔炎合剂提取的工艺

Optimization of the Extraction Processes for stomatitis mixture by the Orthogonal Experiment Design

目的:通过口腔炎合剂的提取工艺研究,确定其最佳工艺条件。方法:以干膏得率和黄芩苷含量为评价指标,采用L9(34)正交实验法,对为最优。结论:该制备工艺科学合理的工艺稳定可靠,提取率高,重现性好,为口腔炎合剂的最佳工艺。

Objective:To filter the best extraction processes for stomatitis mixture by the Orthogonal Experiment Design.Methods:Using L9(34)orthogonal experiment design,using apply extract yield and total flavonoids indicator,to identify the extraction method and solvent for stomatitis mixture by the Orthogonal Experiment Design with the,to investigate the effect of the three main factors,dosage of solvent in extraction process,extracting times and extracting time,which is the extraction efficiency for stomatitis mixture tested by.Results:The extraction process which was adding 10 times amount of water,decoction and extracting for three times,tow hours each time,could obtain high extraction efficiency.Conclusion:The optimized process had higher extraction rate of good stability,reproducibility and was suitable for industrial production.