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应用不同剂量瑞舒伐他汀在ACS患者PIC术后的疗效比较 被引量:1

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摘要 目的:对比分析ACS(急性冠脉综合征)患者PIC术后经不同剂量瑞舒伐他汀治疗的临床疗效。方法:从我院2013年1月~2014年12月行PIC手术治疗的ACS患者中随机抽取106例进行研究,并根据其入院顺序随机分为对照组(53例,经10mg/d常规剂量瑞舒伐他汀治疗)和观察组(53例,经大剂量20mg/d瑞舒伐他汀治疗),对比两组患者治疗前后的生化指标以及心血管事件等不良反应的发生情况。结果:1经治疗,两组患者的hs-CRP、BNP、TG、TC和LDL-C均显著下降,HDL-C均显著上升,治疗前后上述指标差异均具有统计学意义(P<0.05)。治疗后,观察组的hs-CRP、BNP、TG、TC和LDL-C等指标均显著低于对照组,组间差异显著(P<0.05)。2两组患者均无严重不良反应,组间差异不存在统计学意义(P>0.05)。结论:ACS患者PIC术后经大剂量瑞舒伐他汀治疗具有显著效果,可以明显降低患者的炎性反应和BNP水平,而且具有较好的安全性,和常规剂量比较,临床应用价值更高。
出处 《中国医院用药评价与分析》 2016年第S1期102-105,105,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
基金 "黑龙江省卫生计生委科研项目课题编号:2014-209"
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