阴道分泌物唾液酸酶与细菌性阴道病对妊娠结局的影响

Relationship between vaginal sialidase bacteria vaginosis and pregnant result

目的:通过检测阴道分泌物唾液酸酶研究细菌性阴道病(BV)对妊娠结局的影响。方法采用泉池细菌性阴道病快速检测试剂对来我院分娩的382例孕妇进行阴道分泌物唾液酸酶的检测诊断BV,阴道分泌物唾液酸酶阳性诊断为BV,将111例BV阳性列为研究组,271例BV阴性为对照组,对比两组的胎膜早破、早产、新生儿感染发生率。结果382例孕妇中BV检出率为29.06%,研究组的胎膜早破、早产、新生儿感染发生率分别是51.35%、18.02%、11.71%,明显高于对照组的孕妇的15.13%、5.9%、2.21%。两者比较,差异均有非常显著性(P<0.001或P<0.01)。结论阴道分泌物唾液酸酶检测在BV中的阳性率高,是引起胎膜早破、早产、新生儿感染的主要原因,应重视孕期检查时BV的诊断。

Objective To study the relationship among vaginal sialidase, bacterial vaginosis(BV) and resultpregnancy. Methods Vaginal sialidase was measured by quick bacterial vaginosis detection Kit from 382 pregnantwomen in our hospital to labor, the diagnosis of BV was positive of sialidase activity. Incidence of premature ruptureof membranes(PROM), premature delivery, newborn infection 111 cases with BV(study group) and 271 cases normalpregnant(control group) were contrast. Results Positive, s rate with was 29.06% in 382 cases pregnant.Incidenceof premature rupture of membranes, premature delivery, newborn infection in the study group were 51.35 %、18.02 %、11.71 %,the study group were significantly higher than the control group 15.13 %、5.9 %、2.21%。Therewere significant differences between these two groups (P < 0.001orP<0.01).Conclusion Vaginal sialidase activityhas strong relation with bacterial vaginosis. Measuring vaginal sialidase activity is a fast, easy, and useful method todiagnose bacterial vaginosis. It also has relation with PROM, premature delivery, newborn infection .