甲状腺功能亢进症伴肝损害86例临床分析

A Clinical analysis of Hyperthyroidism Leading to Liver Damage

目的:探讨甲亢导致肝损害的临床相关因素。方法回顾性分析86例甲亢性肝损害及同期170例单纯性甲亢的临床资料。结果(1)甲亢导致肝损害的发生率为33.59%。(2)甲亢年龄越大,肝损害的发生率越高(P<0.05)。(3)肝损害的发生率与甲亢患者性别无关(P>0.05)。(4)甲亢性肝损害与甲亢病程密切相关(P<0.01)。(5)甲亢性肝损害患者血清FT3、FT4明显高于单纯性甲亢(P<0.05)。结论甲亢容易导致肝损害,甲亢性肝损害与甲亢患者的年龄、病程及病情密切相关,而与性别无关。

Objective To analyze the clinical relative factors of hyperthyroidism leading to live damage.Methods Clinical history of 86 cases of hyperthyroid with liver damage and 170 cases without liver damage werereviewed. Results (1) The incidence of liver damage accompanied with hyperthyroid was33.59 %; (2) The olderwas the hyperthyroidism patient ,the higher was the incidence of liver damage ( P < 0. 05) ; (3) The incidenceof liver damage was not correlated with gender of hyperthyroidism patient ( P > 0. 05) ; (4) The liver damage wassignificantly correlated with the course of hyperthyroidism( P < 0. 01) ; (5) The serum levels of FT3 and FT4 inhyperthyroid patients with liver damage were significantly higher ( P < 0. 05) . Conclusion Patients withhyperthyroidism are susceptible to liver damage. The seriousness of liver damage is significantly correlated with agecourse and seriousness of hyperthyroidism.