他达那非联合针刺治疗慢性前列腺炎合并勃起功能障碍的疗效评价

Efficacy of tadalafil combined with acupuncture in the treatment of chronic prostatitis with erectile dysfunction

目的探讨他达那非联合针刺治疗慢性前列腺炎合并勃起功能障碍的效果。方法选择郑州市中医院2014年1月—2016年4月收治的慢性前列腺炎伴勃起功能障碍患者60例作为研究对象,随机分为对照组和观察组,各30例。对照组给予单纯左氧氟沙星治疗;观察组在对照组基础上用他达那非联合针刺治疗,4周为1个疗程,两组均治疗3个疗程。治疗后判断临床疗效,采用美国卫生研究院制订的慢性前列腺炎症状指数(NIH)、勃起功能指数(IIEF)评分和生活质量评分进行效果评价。结果观察组总有效率为93.33%,明显高于对照组70.00%,差异有统计学意义(P<0.05);治疗前,两组患者生活质量评分、NIH-CPSI评分、IIEF评分等方面比较,差异无统计学意义(P>0.05);治疗后,观察组患者NIH-CPSI评分明显低于本组治疗前及对照组同期,而生活质量评分和IIEF评分等均明显高于本组治疗前和对照组同期,差异均有统计学意义(均P<0.05);两组患者在治疗过程中,对照组出现1例头痛,观察组出现面红1例,均未采用针对性治疗,短时间后自行消失。结论慢性前列腺炎伴勃起功能障碍者,采用他达那非联合针刺治疗方法效果更好。

Objective To investigate the effect of tadalafil combined with acupuncture on chronic prostatitis combined with erectile dysfunction. Methods Sixty patients with chronic prostatitis and erectile dysfunction admitted in Zhengzhou Hospital of Traditional Chinese Medicine from January 2014 to April2016 were selected as the subjects. The control group was treated with levofloxacin, and the observation group was treated with tadalafil combined with acupuncture. Four weeks for one course, the two groups were treated for 3 courses. After treatment, the clinical efficacy was evaluated by using the chronic prostatitis symptom index(NIH-CPSI), the erectile function index(IIEF) score and the quality of life score. Results The total effective rate of the observation group was 93.33%, which was significantly higher than that of the control group(70.0%, P<0.05). After treatment, the quality of life score, NIH-CPSI score, and IIEF score of the observation group were significantly better than those before treatment and those in the control group(P<0.05). During treatment, 1 case in the control group had a headache, and 1 cases in the observation group got flushed face. However, all the adverse reactions relieved without specific treatment. Conclusion For the treatment of chronic prostatitis with erectile dysfunction, tadalafil combined with acupuncture is a good method to be worth popularizing.