四川地区二胎孕前妇女维生素D水平及影响因素

Maternal vitamin D level and its relevant factors before second pregnancy of women in Sichuan Area

目的了解四川地区二胎孕前妇女的维生素D营养状况及影响因素,为制定改善人群维生素D营养状况和预防缺乏的公共卫生政策提供参考依据。方法选取2016年8月-2017年5月在四川省妇幼保健院二胎门诊就诊和孕前咨询的550名四川省户籍二胎孕前妇女为研究对象,采用酶联免疫吸附法(ELISA)测定血清25羟-维生素D浓度并分析影响因素。结果四川地区二胎孕前妇女维生素D缺乏及不足的比例相对较高,本研究中达到76. 3%。20~25岁和≥36岁年龄组、少数民族、家庭人均年收入<1. 5万,以及体重超重和肥胖孕前妇女的维生素D的水平相对较低,对二胎孕前妇女维生素D水平有影响。结论四川地区二胎孕前妇女维生素D营养状况不佳,应加强人群维生素D缺乏相关知识的健康宣教,制定主动干预措施,定期评估维生素D的营养状况并指导其有效合理的补充,为后续的营养干预及相关卫生政策制定提供依据。

Objective To understand the nutritional status and influencing factors of vitamin D in women before second pregnancy in Sichuan province,and to provide reference for formulating public health policies to improve the nutritional status of vitamin D and prevent its deficiency.Methods A total of 550 women with household registration in Sichuan Province before pregnancy were selected from the second child clinic and pre-pregnancy consultation in Sichuan Maternal and Child Health Hospital from August 2016 to May2017.The serum 25-hydroxy-vitamin D concentration was determined by enzyme-linked immunosorbent assay(EUSA).Results The proportion of vitamin D deficiency and insufficiency in women before second pregnancy was relatively high.Age,ethnicity,family income and body weight per capita affected the level of vitamin D.Results The percentage of vitamin D deficiency was relatively high in Sichuan women before the second pregnancy,reaching 76.3%in this study.The vitamin D levels were relatively low in 20-25-year-old and≥36-year-old women,ethnic minorities,families with an average annual income of more than 15,000,and overweight and obese women before pregnancy.It has an effect on the level of vitamin D in women before second pregnancy.Conclusion The vitamin D nutritional status of women with second child before pregnancy in Sichuan is poor,Health education on vitamin D deficiency should be strengthened and active intervention measures should be formulated.It is necessary to regularly evaluate the nutritional status of vitamin D and guide its effective and reasonable supplement,so as to provide a basis for follow-up nutrition intervention and related health policy formulation.