聚乳酸微球表面的氨等离子体表面改性

Surface Modification of Poly (d,l-lactic acid) Microspheres by Ammonia Low-Temperature Plasma

分别以聚乙烯醇和壳聚糖溶液为外水相制备了疏水性聚乳酸(PDLLA)微球,并采用氨气氛下低温等离子体技术进行修饰,以产生较高的亲水性表面。以X-光电子能谱(XPS)、接触角和薄层层析法(TLW)研究PDLLA微球表面特性及亲水性。研究结果表明,含氮基团能通过低温氨气氛等离子体处理而连接到微球表面。微球表面的亲水性与未经处理的微球相比有所提高,对于表面改性后的微球,其接触角明显降低。

The hydrophobic poly (d,l-lactic acid)(PDLLA) micropsheres were prepared in poly vinyl alcohol and chitosan solution respectively as aqueous phase,and then modified by low-temperature plasma technique.Surfaces of microspheres treated by ammonia plasma were characterized with X-ray photoelectron spectroscopy (XPS),and their wettability was studied by Contact Angle and Thin Layer Wicking measurements.It is obtained that groups contained nitrogen atoms could be introduced into the surfaces of the microspheres surfaces by low-temperature ammonia plasma.The hydrophilic character of the modified surfaces was increased in comparison with that of the parent microspheres.The contact angle for modified PDLLA microspheres were reduced apparently.