玉屏风口服液的质量标准研究

Study on quality standard of Yupingfeng Oral Liquid

目的 :建立玉屏风口服液 (黄芪、防风、白术 )的质量标准。方法 :用薄层色谱法对黄芪、防风、白术进行了定性鉴别 ;用高效液相色谱 蒸发光散射检测器 (HPLC ELSD)法测定了口服液中黄芪甲苷的含量。结果 :定性鉴别分离度好 ,专属性强 :含量测定黄芪甲苷的平均加样回收率为 97.75 % ,RSD为 1.31%。结论 :方法简便准确、灵敏度高 ,可用于玉屏风口服液的质量控制。

Objective: To established a method for the quality standard of Yupingfeng Oral Liquid(Radix Astragali, Radix Saposhnikoviae and Rhizoma Atractylodis Macrocephalae). Methods:Radix Astragali, Radix Saposhnikoviae and Rhizoma Atractylodis Macrocephalae in oral liquid were identified by TLC. The content of astragaloside IV was determined by HPLC-ELSD. Results:The study showed that spots of samples on TLC can be well separated and the method had strong specificity. The average recovery was 97.75% and RSD was 1.31%. Conclusion:The method is simple, sensitive and accurate. It can be used for quality control of Yupingfeng Oral Liquid.