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肿瘤化学预防药物的临床前筛选体系 被引量：2

Preclinical screening tests of tumor chemoprevention agents
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摘要 简要描述了国外在开展肿瘤化学预防药物研究时所使用的一系列临床前筛选试验方法 ,这些方法组成了一个比较系统的肿瘤化学预防药物筛选体系 ,这一体系将会在我国的癌症预防药物特别是中药癌症预防药物研究中起到借鉴作用。 The preclinical screening tests used to research tumor chemoprevention agents by overseas research groups were described. These tests composed a screening system for evaluating tumor chemopreventive agents and should be used to screen tumor prevention agents from traditional Chinese herbs.
作者 易宗春 王钊
机构地区 清华大学生物科学与技术系
出处 《中国药理学通报》 CAS CSCD 北大核心 2003年第7期746-750,共5页 Chinese Pharmacological Bulletin
基金 国家自然科学基金 No 30 2 71593 清华大学基础研究基金 NoJC2 0 0 2 0 4 6 中国博士后科学基金资助项目
关键词 致癌 癌症/肿瘤 化学预防 临床前筛选 carcinogenesis cancer/tumor chemoprevention preclinical screening
分类号 R730.52 [医药卫生—肿瘤] R730.53 [医药卫生—肿瘤]
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参考文献19

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同被引文献16

  • 1郑晓亮,刘雪莉,钱伯初.植物提取物诱导肿瘤细胞凋亡机制研究进展[J].中国药理学通报,2004,20(11):1201-1205. 被引量：16
  • 2Mack Roach Ⅲ,孔琳.前列腺癌:近期研究结果和新方向[J].中国癌症杂志,2007,17(3):188-192. 被引量：3
  • 3武国海,周彩红,王明伟.前列腺癌治疗药物的研究新进展[J].中国新药杂志,2007,16(17):1330-1336. 被引量：4
  • 4Hu Y,Chen L,Yi C,Yang F Chen J. Experimental study on inhibitory effects of diallyl sulfide on growth and invasion of human osteosarcoma MG-63cells[J].Journal of Huazhong University of Science and Technology(Medical Science),2012,(04):581-585.doi:10.1007/s11596-012-1000-z.
  • 5Feng Y,Zhu X,Wang Q,Jiang Y Shang H Cui L Cao Y. Allicin enhances host pro-inflammatory immune responses and protects against acute murine malaria infection[J].Malaria Journal,2012,(01):268.
  • 6Awodele O,Olayemi SO,Adeyemo TA,Sanya TA Dolapo DC. Use of Complementary Medicine Amongst Patients on Antiretroviral Drugs in an HIV Treatment Centre in Lagos,Nigeria[J].Curr Drug Saf,2012,(02):120-125.
  • 7Ritota M,Casciani L,Han BZ,Cozzolino S,Leita L,Sequi P,Valentini M. Traceability of Italian garlic (Allium sativum L.) by means of HRMAS-NMR spectroscopy and multivariate data analysis[J].Food Chemistry,2012,(02):684-693.
  • 8Zhang L,Zhang H,Miao Y,Wu S Ye H Yuan Y. Protective effect of allicin against acrylamide-induced hepatocyte damage in vitro and in vivo[J].Food and Chemical Toxicology,2012,(09):3306-3312.
  • 9Cha JH,Choi YJ,Cha SH,Choi CH Cho WH. Allicin inhibits cell growth and induces apeptosis in U87MG human glioblastoma cells through an ERK-dependent pathway[J].Oncology Reports,2012,(01):41-48.
  • 10姜承和.实验动物在肿瘤研究中的选择和应用[A]北京:人民卫生出版社,19971092-1095.

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中国药理学通报
2003年 第7期

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