重型颅脑损伤并发多器官功能障碍综合征的危险因素分析

Analysis of risk factors of multiple organ dysfunction syndrome following severe craniocerebral injury

目的 探讨重型颅脑损伤后多器官功能障碍综合征 (MODS)的临床危险因素。方法 回顾性分析我院 3年来收治的重型颅脑损伤 1 38例 ,并发MODS 4 6例 (33.3% ) ,对其中 1 2种相关因素进行分析。结果入院时GCS评分低、广泛的脑实质损伤、脑疝的发生、低血压、低氧血症、合并其他重要脏器损伤、大量输血及严重高血糖反应与MODS的发生密切相关 ,同时具有 2种以上危险因素者MODS发病率明显增高。结论 对具有高危因素尤其是多种因素并存者应警惕MODS的发生。

Objective To study the risk factors of multiple organ dysfunction syndrome (MODS) after severe craniocerebral injury(SCI).Methods One hundred and thirty eight patients with SCI admitted to our hospital during the last 3 years were retrospectively analyzed,and 46 patients followed by MODS.Twelve risk factors were chosen.ResultsThe study showed that low GCS score,diffuse brain parenchymal damage,herniation,low blood pressure,low blood oxygen,with other important orgen severe injury,large quantity blood transfusion(≥2000ml/24h) and hyperglycemia(≥ 11.0mmol/L) were easily complicated by MODS. The incidence of MODS was significantly increased in the patients with 2 or more risk factors.Conclusion For the patients with high risk factors more attention should be paid to the occurrence of MODS.