循证晚期妊娠母血及脐血铁蛋白水平的相关性

Study on the correlativity of the level of serum ferritin with pregnant women and fetal at trimester

目的 研究晚期妊娠妇女血清及胎儿脐血中铁蛋白水平的变化并探讨其相关性。方法 根据血红蛋白 (Hb)水平的不同各选取 2 5例孕足月妇女定为A组 (10 0 g/L～ 10 5g/L)、B组 (10 5 g/L～ 110 g/L)、C组 (Hb≥ 110g/L)。分别测定母血、脐血铁蛋白水平。结果 C组母血、脐血铁蛋白水平分别为 (19.0 9± 4 .0 8) μg/L和 (199.6 0± 6 1.0 4 ) μg/L ,高于A、B组 ,差异有显著性 (P <0 .0 5 ) ;Hb在 10 0g/L～ 110 g/L范围内母血与脐血的铁蛋白水平呈正相关 (P <0 .0 1)。结论 通过对母血铁蛋白的测定可以了解胎儿体内的贮铁水平 ;将正常孕妇血红蛋白值评判标准以往的 >10 0 g/L提高为 >110g/L ,有利于及时发现和治疗铁缺乏期的孕妇。

Objective: To study the serum ferritin(SF) changes and the correlativity with pregnant women and fetal at trimeSter.Methods: All the 75 pregnant women at trimeter were divided into three groups according to the level of hemoglobulim(Hb), A:100g/L～105g/L, B:105g/L～110g/L, C:>110g/L.The SF of both mothers and babies were measured by using chemiluminescent immunoassay(CLIA). Results: Mothers'SF level of C group was (19.09±4.08)μg/L, babies'SF level of C groups was ( 199.60±61.04)μg/L.C group was the highest of both A and B groups(P<0.05). Mothers'SF lever showed positive correlation with their babies'when Hb was in 100g/L～110g/L(P<0.01). Conclusion These date suggest that detecting the SF level of mothers can do us some favour in determine the stored iron level of babies.Improve the diagnosis standard of Hb in normal pregnant women from 100g/L to 110g/L, could be of value in diagnosis and treatment of those iron deficiency(ID) patients.